--- title: Highpoint Hotel date: 2026-01-20T16:51:00-06:00 author: Matt Barthel canonical_url: "https://www.experiencesiouxfalls.com/listing/highpoint-hotel" section: Listings --- ![Exterior of the Sanford Children's Hospital and High Point Hotel](https://d3bs6yihjcg6lz.cloudfront.net/generalUploads/IMG_4197.jpeg?mode=crop&pos=center-center&w=550&h=241&q=98&f=webp&c=31afddc8&v=4f3b88d69a849bd9b1b95c35d437963cc06f6f1e8d1fadbf2f987e7f16c65135) # Highpoint Hotel ![](/assets/images/icons/location-pin.svg)Address [ 1530 W 22nd St Sioux Falls, SD 57105 ](https://www.google.com/maps/dir/?api=1&destination=1530%20W%2022nd%20St%20Sioux%20Falls%2C%20SD%2057105) ![](/assets/images/icons/desktop.svg)Website [Visit Website for Highpoint Hotel](https://www.thehighpointhotel.com/) ![](/assets/images/icons/phone-alt-pink.svg)Contact [(605) 404-4500](tel:(605)%20404-4500) Highpoint Hotel, nestled within the renowned Sanford Hospital in Sioux Falls, redefines elevated comfort with a sanctuary‑like atmosphere designed for discerning guests. This intimate 56 room retreat blends refined style with thoughtful serenity, offering plush accommodations, sophisticated finishes, and a level of hospitality grounded in genuine care. Highpoint provides an oasis of calm where guests—whether travelers, families, or visiting professionals—experience exceptional comfort, seamless convenience, and a stay that feels effortlessly indulgent. ![](https://d3bs6yihjcg6lz.cloudfront.net/generalUploads/IMG_4196.jpeg?mode=crop&pos=center-center&w=612&h=335&q=98&f=webp&c=c5dbac33&v=ae1ff6684237efc1d6e8c6844f0005a79a00b6d74db36bce3cdff83a1f81160c) ![](https://d3bs6yihjcg6lz.cloudfront.net/generalUploads/IMG_4195.jpeg?mode=crop&pos=center-center&w=612&h=335&q=98&f=webp&c=c1a7d5dc&v=fde3bd961b1f276a221ecc43e792fe3d68b40d5c64949585df1c214f6b7b2aa8) ![](https://d3bs6yihjcg6lz.cloudfront.net/generalUploads/IMG_4194.jpeg?mode=crop&pos=center-center&w=612&h=335&q=98&f=webp&c=e8f4b914&v=fbb7dee0c71e50ab6a77d3b2c600c0facb72dc55064d431059c5ad9c437ad0d2) ## ![Trip Advisor Reviews](/assets/images/tripadvisor-logo.svg) ### TripAdvisor Traveler Rating ![Trip Advisor Rating: 4.9](https://www.tripadvisor.com/img/cdsi/img2/ratings/traveler/5.0-14796-5.svg) [88 Reviews](https://www.tripadvisor.com/Hotel_Review-g54805-d33989447-Reviews-The_Highpoint_Hotel-Sioux_Falls_South_Dakota.html?m=14796) | [Write a Review](https://www.tripadvisor.com/UserReview-g54805-d33989447-The_Highpoint_Hotel-Sioux_Falls_South_Dakota.html?m=14796)--- #### Highpoint was a high point ![5 star rating](https://www.tripadvisor.com/img/cdsi/img2/ratings/traveler/s5.0-14796-5.svg) Reviewed October 26, 2026 Beautiful boutique hotel that is part of the Sanford medical complex. Large rooms with floor to ceiling windows. [Read Full Review for Highpoint was a high point (On TripAdvisor) ](https://www.tripadvisor.com/ShowUserReviews-g54805-d33989447-r1083299260-The_Highpoint_Hotel-Sioux_Falls_South_Dakota.html?m=14796#review1083299260) --- #### Great location for college events ![5 star rating](https://www.tripadvisor.com/img/cdsi/img2/ratings/traveler/s5.0-14796-5.svg) Reviewed October 25, 2026 Clean, new and great staff that were very friendly and helpful. The location is great! Close to college campuses for events. [Read Full Review for Great location for college events (On TripAdvisor) ](https://www.tripadvisor.com/ShowUserReviews-g54805-d33989447-r1083208551-The_Highpoint_Hotel-Sioux_Falls_South_Dakota.html?m=14796#review1083208551) --- #### Loved it! ![5 star rating](https://www.tripadvisor.com/img/cdsi/img2/ratings/traveler/s5.0-14796-5.svg) Reviewed October 25, 2026 We came to town for a concert and honestly wish we had more time to stay in our suite. It was so nice and clean. We loved the layout. [Read Full Review for Loved it! (On TripAdvisor) ](https://www.tripadvisor.com/ShowUserReviews-g54805-d33989447-r1083208224-The_Highpoint_Hotel-Sioux_Falls_South_Dakota.html?m=14796#review1083208224) --- #### Great stay while visiting Sanford ![5 star rating](https://www.tripadvisor.com/img/cdsi/img2/ratings/traveler/s5.0-14796-5.svg) Reviewed October 23, 2026 We stayed at The Highpoint Hotel for my pre and post operation. Being attached to the Sanford Medical Center, makes the hotel an ideal place to stay. The rooms are well maintained. The entire staff... [Read Full Review for Great stay while visiting Sanford (On TripAdvisor) ](https://www.tripadvisor.com/ShowUserReviews-g54805-d33989447-r1082934646-The_Highpoint_Hotel-Sioux_Falls_South_Dakota.html?m=14796#review1082934646) --- #### Very n8ce hotel! ![4 star rating](https://www.tripadvisor.com/img/cdsi/img2/ratings/traveler/s4.0-14796-5.svg) Reviewed October 20, 2026 Just stayed there as we have family in Sanford hospital, Very clean hotel you can tell its new Mindy was awesome help , we had the 6 floor suite, it was beautiful and big 1st class room, we would... [Read Full Review for Very n8ce hotel! (On TripAdvisor) ](https://www.tripadvisor.com/ShowUserReviews-g54805-d33989447-r1082543470-The_Highpoint_Hotel-Sioux_Falls_South_Dakota.html?m=14796#review1082543470) ## Services & Amenities - ADA Compliant - Fitness Facilities - Handicapped Accessible - High Speed Internet/Wireless Internet (Free) - Lounge - Microwave and/or Refrigerator in Room - Guest Laundry ## What's Nearby - ![](/assets/images/icons/map-star.svg)Highpoint Hotel - [![](/assets/images/icons/location-pin-numbered.svg)1 Home2 Suites by Hilton- Sanford Medical Center](https://www.experiencesiouxfalls.com/listing/home2-suites-by-hilton-sanford-medical-center) - [![](/assets/images/icons/location-pin-numbered.svg)2 Center Inn](https://www.experiencesiouxfalls.com/listing/center-inn) - [![](/assets/images/icons/location-pin-numbered.svg)3 Valley Inn](https://www.experiencesiouxfalls.com/listing/valley-inn) ![Blarney Stone HOP](https://d3bs6yihjcg6lz.cloudfront.net/generalUploads/Blarney_Stone_HOP813-102.jpg?mode=crop&pos=center-center&w=556&h=427&q=98&f=webp&c=c652570e&v=23bcee96588f71860c65cb1631f90268ad8ff6edc98f7f2b7b94a6f6fe7c0c42) [Places to Stay ](https://www.experiencesiouxfalls.com/places-to-stay) ![Hyatt Place exterior](https://d3bs6yihjcg6lz.cloudfront.net/generalUploads/Hyatt-Place-exterior.jpg?mode=crop&pos=center-center&w=556&h=427&q=98&f=webp&c=2a2db221&v=ba65e8097e9f422240b36c713b929ce38801e6cabf8bf41e1631e3588765b1f3) [All Hotels ](https://www.experiencesiouxfalls.com/places-to-stay/hotels)