605 Pop Culture Con

The 605 Pop Culture Con, presented by Voices Against Cancer, is an annual celebration of fandom, creativity, and compassion, taking place on June 28th and 29th, 2025, at the Sioux Falls Convention Center in Sioux Falls, South Dakota. This premier pop culture event brings together fans, celebrities, voice actors, artists, and vendors to honor beloved franchises like Star Wars, Lord of the Rings, Marvel and more, while rallying around a critical cause: fighting childhood cancer

Organized by the nonprofit Voices Against Cancer, the 605 Pop Culture Con is more than just a convention—it’s a powerful fundraiser dedicated to raising awareness and funds for pediatric cancer research and support for families affected by the disease. All proceeds from door entries, autographs, photo opportunities, and musical performances directly benefit initiatives that assist families dealing with pediatric cancer and advance research to improve survival rates and treatments. The event highlights the stark reality that childhood cancer remains the leading cause of disease-related death among children in the U.S., with only a small fraction of federal cancer research funding allocated to pediatric cases, making community efforts like this vital.

Attendees can expect an unforgettable experience featuring appearances by iconic celebrities and voice actors, interactive photo ops, a vibrant vendor hall filled with pop culture merchandise, and unique silent auction items. The convention also partners with local efforts, such as the Sioux Empire St. Baldrick’s Head Shaving Event, to amplify support for children battling cancer. By attending, participants not only immerse themselves in a festival of fandom but also contribute to a movement that strives to #GiveKidsAVoice, ensuring a brighter future for the youngest fighters.

Join thousands of fans and make a difference at the 605 Pop Culture Con, where pop culture and purpose collide for an inspiring weekend of fun and impact.

Weekend Passes: $30